週次 |
日期 |
單元主題 |
第1週 |
09/14 |
a. Course introduction, overview of genetic epidemiology
b. Mendelian inheritance and its extensions/陳為堅 |
第2週 |
09/21 |
Hardy-Weinberg equilibrium and estimation of gene frequency/陳為堅 |
第3週 |
09/28 |
Linkage disequilibrium and estimation of haplotype frequency/陳為堅 |
第4週 |
10/05 |
Genetic risks and kinship coefficient/陳為堅 |
第5週 |
10/12 |
a. 遺傳流行病學 (陳為堅,2015) (公共衛生學-中冊第20章,修訂五版。台北市: 國立臺灣大學出版中心; 2015:167-202)
b. Video learning
|
第6週 |
10/19 |
Genetic linkage, recombination fraction, and mapping function/陳為堅 |
第7週 |
10/26 |
Practice: Software FBAT and GCTA/ TA陳佳蓓 |
第8週 |
11/02 |
Genetic model for quantitative traits/陳為堅 |
第9週 |
11/09 |
Recurrence risk ratio and genotype relative risk/陳為堅 |
第10週 |
11/16 |
Linkage analysis for categorical and quantitative traits/陳為堅 |
第11週 |
11/23 |
Guest Lecture: Genome-wide association study (GWAS) /郭柏秀 |
第12週 |
11/30 |
Practice: Software PLINK and PRSice/TA陳佳蓓 蕭伯璋 |
第13週 |
12/07 |
Analysis for gene expression levels and gene dosage effect/陳為堅 |
第14週 |
12/14 |
Guest Lecture: Genetic analysis to incorporate rare variants/林菀俞 |
第15週 |
12/21 |
Random genetic drift /陳為堅 |
第16週 |
12/28 |
Guest Lecture: Applications of bioinformatics in precision medicine/陳璿宇 |
第17週 |
01/04 |
Students' Presentation (I) |
第18週 |
01/11 |
Students' Presentation (II) |